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1

Synthesis and pharmacological evaluation of novel derivatives of anti-inflammatory drugs with increased antioxidant and anti-inflammatory activities

Angeliki P. Kourounakis, Dimitrios Galanakis, Karyofillis Tsiakitzis, Eleni A. Rekka, Panos N. Kourounakis

Journal:

Drug Development Research

Year:

1999

Language:

english

File:

PDF, 186 KB

english, 1999

2

Anti-inflammatory Properties of New Adamantane Derivatives. Design, Synthesis, and Biological Evaluation

Ekaterini Antoniadou-Vyza, Nikos Avramidis, Angeliki Kourounakis, Lygeri Hadjipetrou

Journal:

Archiv der Pharmazie

Year:

1998

Language:

english

File:

PDF, 115 KB

english, 1998

3

Design of more potent squalene synthase inhibitors with multiple activities

Angeliki P. Kourounakis, Alexios N. Matralis, Anastasios Nikitakis

Journal:

Bioorganic & Medicinal Chemistry

Year:

2010

Language:

english

File:

PDF, 1.34 MB

english, 2010

4

QSAR of substituted morpholines with antioxidant and squalene synthase inhibitory activity

Anastasios Nikitakis, Angeliki P. Kourounakis

Journal:

Medicinal Chemistry Research

Year:

2011

Language:

english

File:

PDF, 362 KB

english, 2011

5

Inverse agonism at G protein-coupled receptors: (patho)physiological relevance and implications for drug discovery

Rianne A F De Ligt, Angeliki P Kourounakis, Ad P IJzerman

Journal:

British Journal of Pharmacology

Year:

2000

Language:

english

File:

PDF, 196 KB

english, 2000

6

Design, synthesis and biological evaluation of novel β-substituted indol-3-yl ethylamido melatoninergic analogues

K. Iakovou, A. Varvaresou, A. P. Kourounakis, K. Stead, D. Sugden, A. Tsotinis

Journal:

Journal of Pharmacy and Pharmacology

Year:

2002

Language:

english

File:

PDF, 280 KB

english, 2002

7

Compounds against inflammation and oxidative insult as potential agents for neurodegenerative disorders

Christos M. Doulgkeris, Ioanna C. Siskou, Nikoletta Xanthopoulou, Vassiliki Lagouri, Constantina Kravaritou, Phaedra Eleftheriou, Panos N. Kourounakis, Eleni A. Rekka

Journal:

Medicinal Chemistry Research

Year:

2012

Language:

english

File:

PDF, 430 KB

english, 2012

8

Liver Ultrastructure During Acute Stress

Salas, Milagros, Tuchweber, Beatriz, Kourounakis, P.

Journal:

Pathology - Research and Practice

Year:

1980

Language:

english

File:

PDF, 6.49 MB

english, 1980

9

Antinociceptive Properties of 1,8-Cineole and β-Pinene, from the Essential Oil of Eucalyptus camaldulensis Leaves, in Rodents

Liapi, Charis, Anifantis, Georgios, Chinou, Ioanna, Kourounakis, Angeliki, Theodosopoulos, Stelios, Galanopoulou, Panagiota

Journal:

Year:

2007

Language:

english

File:

PDF, 618 KB

english, 2007

10

Antinociceptive Properties of 1,8-Cineole and β-Pinene, from the Essential Oil of Eucalyptus camaldulensis Leaves, in Rodents

Liapi, C., Anifandis, G., Chinou, I., Kourounakis, A., Theodosopoulos, S., Galanopoulou, P.

Journal:

Year:

2008

File:

PDF, 20 KB

2008

11

Morpholine as a privileged structure: A review on the medicinal chemistry and pharmacological activity of morpholine containing bioactive molecules

Kourounakis, Angeliki P., Xanthopoulos, Dimitrios, Tzara, Ariadni

Journal:

Medicinal Research Reviews

Year:

2019

Language:

english

File:

PDF, 3.80 MB

english, 2019

12

Elucidation of structure–activity relationships of 2-amino-3-benzoylthiophenes: Study of their allosteric enhancing vs. antagonistic activity on adenosine A1 receptors

Angeliki P. Kourounakis, Pieter A.M. Van der Klein, Ad P. Ijzerman

Journal:

Drug Development Research

Year:

2000

Language:

english

File:

PDF, 243 KB

english, 2000

13

Research on the pharmacochemistry of some GABA and valproic acid derivatives

G.V. Rekatas, Ek. Tani, V.J. Demopoulos, P.N. Kourounakis

Journal:

Drug Development Research

Year:

2000

Language:

english

File:

PDF, 124 KB

english, 2000

14

Alkannin and Shikonin: Effect on Free Radical Processes and on Inflammation - A Preliminary Pharmacochemical Investigation

Angeliki P. Kourounakis, Andreana N. Assimopoulou, Vassilios P. Papageorgiou, Antonis Gavalas, Panos N. Kourounakis

Journal:

Archiv der Pharmazie

Year:

2002

Language:

english

File:

PDF, 99 KB

english, 2002

15

Lipophilicity of Some Substituted Morpholine Derivatives Synthesized as Potential Antinociceptive Agents

Eleni Rekka, Stavros Retsas, Vassilis J. Demopoulos, Panos N. Kourounakis

Journal:

Archiv der Pharmazie

Year:

1990

Language:

english

File:

PDF, 357 KB

english, 1990

16

Induction of Drug Metabolism can be a Homeostatic Response

Panos N. Kourounakis, Eleni Rekka

Journal:

Archiv der Pharmazie

Year:

1991

Language:

english

File:

PDF, 301 KB

english, 1991

17

Pharmacochemistry of Novel Aminoketone Phthalimide, Δ4-Tetrahydrophthalimide, and Arylsuccinimide Derivatives with Local Anaesthetic Activity

Eleni Sotiropoulou, Panos N. Kourounakis

Journal:

Archiv der Pharmazie

Year:

1994

Language:

english

File:

PDF, 405 KB

english, 1994

18

Synthesis of GABA-Valproic Acid Derivatives and Evaluation of Their Anticonvulsant and Antioxidant Activity

George V. Rekatas, Ekaterini Tani, Vassilis J. Demopoulos, Panos N. Kourounakis

Journal:

Archiv der Pharmazie

Year:

1996

Language:

english

File:

PDF, 582 KB

english, 1996

19

Effect of Guaiazulene on Some Cytochrome P450 Activities. Implication in the Metabolic Activation and Hepatotoxicity of Paracetamol

Angeliki P. Kourounakis, Eleni A. Rekka, Panos N. Kourounakis

Journal:

Archiv der Pharmazie

Year:

1997

Language:

english

File:

PDF, 499 KB

english, 1997

20

Stress and Active Oxygen Species – Effect of α-Tocopherol on Stress Response

Karyofyllis Tsiakitzis, Angeliki P. Kourounakis, Ekaterini Tani, Eleni A. Rekka, Panos N. Kourounakis

Journal:

Archiv der Pharmazie

Year:

2005

Language:

english

File:

PDF, 102 KB

english, 2005

21

Antioxidant Activity of Newly Synthesized 2,7-Diazaphenothiazines

Beata Morak-Młodawska, Krystian Pluta, Alexios N. Matralis, Angeliki P. Kourounakis

Journal:

Archiv der Pharmazie

Year:

2010

Language:

english

File:

PDF, 542 KB

english, 2010

22

Cu(II) complex of an estradiol derivative with potent anti-inflammatory properties

Dimitris M. Spyriounis, Eleni Rekka, Vassilis J. Demopoulos, Panos N. Kourounakis

Journal:

Archiv der Pharmazie

Year:

1991

Language:

english

File:

PDF, 341 KB

english, 1991

23

The effect of a cobra venom factor on complement and adjuvant-induced disease in rats

Lygeri Kourounakis, R A Nelson Jr, Dr. M A Kupusta

Journal:

Arthritis & Rheumatism

Year:

1973

Language:

english

File:

PDF, 337 KB

english, 1973

24

Virazole and adjuvant-induced disease in rats

Lygeri Kourounakis, Mavis Young-Rodenchuk, Morton A. Kapusta

Journal:

Arthritis & Rheumatism

Year:

1977

Language:

english

File:

PDF, 78 KB

english, 1977

25

ChemInform Abstract: Antiinflammatory Properties of New Adamantane Derivatives. Design, Synthesis, and Biological Evaluation.

E. ANTONIADOU-VYZA, N. AVRAMIDIS, A. KOUROUNAKIS, L. HADJIPETROU

Journal:

Year:

1998

File:

PDF, 36 KB

1998

26

ChemInform Abstract: Allosteric Modulation of G Protein-Coupled Receptors

Ad Ijzerman, Angeliki Kourounakis, Pieter van der Klein

Journal:

Year:

2001

File:

PDF, 25 KB

2001

27

Synthesis and Antifungal and Antioxidant Properties of Some New 5-Substituted-4-amino(or aryl)-3-mercapto-4(H)-1,2,4-triazoles.

Panagiotis Marakos, Spyroula Papakonstantinou-Garoufalias, Ekaterini Tani, Panos N. Kourounakis, George Afhanasiou, Aikaterini Chytyroglou-Lada

Journal:

Year:

2002

File:

PDF, 29 KB

2002

28

Synthesis of New Azulene Derivatives and Study of Their Effect on Lipid Peroxidation and Lipoxygenase Activity.

Eleni Rekka, Michael Chrysselis, Ioanna Siskou, Angeliki Kourounakis

Journal:

Year:

2003

File:

PDF, 140 KB

2003

29

Synthesis and Activity on Free Radical Processes and Inflammation of 9,10-Dihydro-5,8-dimethoxy-triptycene-quinones.

Nikoletta J. Xanthopoulou, Angeliki P. Kourounakis, Spyros Spyroudis, Panos N. Kourounakis

Journal:

Year:

2003

File:

PDF, 125 KB

2003

30

Synthesis and Pharmacological Evaluation of Amide Conjugates of NSAIDs with L-Cysteine Ethyl Ester, Combining Potent Antiinflammatory and Antioxidant Properties with Significantly Reduced Gastrointestinal Toxicity.

Dimitrios Galanakis, Angeliki P. Kourounakis, Karyophyllis C. Tsiakitzis, Christos Doulgkeris, Eleni A. Rekka, Antonios Gavalas, Constantina Kravaritou, Christos Charitos, Panos N. Kourounakis

Journal:

Year:

2004

Language:

english

File:

PDF, 13 KB

english, 2004

31

Allosteric modulation of the rat adenosine A1 receptor: Differential effects on agonist and antagonist binding

Angeliki P. Kourounakis, Corine Visser, Miriam de Groote, Ad P. IJzerman

Journal:

Drug Development Research

Year:

2000

Language:

english

File:

PDF, 156 KB

english, 2000

32

Effect of various steroids and ACTH on plasma levels of zoxazolamine and dicumarol

P. Kourounakis, S. Szabo, J. Werringloer, H. Selye

Journal:

Journal of Pharmaceutical Sciences

Year:

1973

Language:

english

File:

PDF, 325 KB

english, 1973

33

Effect of various steroids and ACTH on distribution of zoxazolamine in rats

P. Kourounakis, S. Szabo, H. Selye

Journal:

Journal of Pharmaceutical Sciences

Year:

1973

Language:

english

File:

PDF, 441 KB

english, 1973

34

Structural features and protective activity of dexamethasone and pregnenolone-16α-carbonitrile

A. Terzis, P. Kourounakis, T. Theophanides

Journal:

Journal of Pharmaceutical Sciences

Year:

1976

Language:

english

File:

PDF, 337 KB

english, 1976

35

Influence of steroids and stress on toxicity and disposition of tetraethylammonium bromide

Panos Kourounakis, Hans Selye

Journal:

Journal of Pharmaceutical Sciences

Year:

1976

Language:

english

File:

PDF, 331 KB

english, 1976

36

Alterations induced in distribution and in vivo metabolism of imipramine by pregnenolone-16α-carbonitrile

Sheldon Brookman, Panos Kourounakis

Journal:

Journal of Pharmaceutical Sciences

Year:

1977

Language:

english

File:

PDF, 344 KB

english, 1977

37

Laser Raman spectra of some representative hormonal steroids

George Pouskouleli, Ian S. Butler, Panos Kourounakis

Journal:

Journal of Molecular Structure

Year:

1983

Language:

english

File:

PDF, 452 KB

english, 1983

38

Solid and solution behavior of sulphonylurea complexes with ions of IIa group metals. Molecular modeling of K[Zn(ClCH4SO2NCONHC3H7)3] and Action of zinc-sulphonylurea complexes as hypoglycemic agents

A.G. Hatzidimitriou, D.P. Kessissoglou, G.E. Manoussakis, P.N. Kourounakis, G. Economidis

Journal:

Journal of Inorganic Biochemistry

Year:

1990

Language:

english

File:

PDF, 855 KB

english, 1990

39

Synthesis, physicochemical properties and biological studies of some substituted 2-alkoxy-4-methyl-morpholines

Eleni Rekka, Panos Kourounakis

Journal:

European Journal of Medicinal Chemistry

Year:

1989

Language:

english

File:

PDF, 584 KB

english, 1989

40

Structural considerations of the 16-cyano and related pregnenolones on their drug metabolic inducing activity

PN Kourounakis, E Rekka

Journal:

European Journal of Medicinal Chemistry

Year:

1990

Language:

english

File:

PDF, 409 KB

english, 1990

41

Synthesis and biological studies of some novel antiinflammatory aryl-hydroxy-amino-ketones

D Hadjipavlou-Litina, E Rekka, L Hadjipetrou-Kourounakis, P Kourounakis

Journal:

European Journal of Medicinal Chemistry

Year:

1991

Language:

english

File:

PDF, 559 KB

english, 1991

42

Estrogen-cis-dichloroethylenediamineplatinum (II) complexes: synthesis and evaluation of binding affinity for estrogen receptors and the effect on breast cancer MCF-7 cells

DM Spyriounis, VJ Demopoulos, PN Kourounakis, D Kouretas, A Kortsaris, O Antonoglou

Journal:

European Journal of Medicinal Chemistry

Year:

1992

Language:

english

File:

PDF, 492 KB

english, 1992

43

Ionization constants, lipophilicity and biological studies of some novel aryl-(amino or hydroxy)ethyl amino ketones with anti-inflammatory activity

D Hadjipavlou-Litina, E Rekka, L Hadjipetrou-Kourounakis, PN Kourounakis

Journal:

European Journal of Medicinal Chemistry

Year:

1992

Language:

english

File:

PDF, 591 KB

english, 1992

44

Novel N-substituted 3-aminosteroids which exhibit anti-inflammatory properties and influence free radical processes

DM Spyriounis, E Tani, E Rekka, VJ Demopoulos, PN Kourounakis

Journal:

European Journal of Medicinal Chemistry

Year:

1993

Language:

english

File:

PDF, 541 KB

english, 1993

45

Synthesis of chroman analogues of lipoic acid and evaluation of their activity against reperfusion arrhythmias

Maria Koufaki, Anastasia Detsi, Elissavet Theodorou, Christina Kiziridi, Theodora Calogeropoulou, Athanasios Vassilopoulos, Angeliki P. Kourounakis, Eleni Rekka, Panos N. Kourounakis, Catherine Gaitan

Journal:

Bioorganic & Medicinal Chemistry

Year:

2004

Language:

english

File:

PDF, 305 KB

english, 2004

46

Nitric oxide releasing derivatives of tolfenamic acid with anti-inflammatory activity and safe gastrointestinal profile

George N. Ziakas, Eleni A. Rekka, Antonios M. Gavalas, Phaedra T. Eleftheriou, Karyofillis C. Tsiakitzis, Panos N. Kourounakis

Journal:

Bioorganic & Medicinal Chemistry

Year:

2005

Language:

english

File:

PDF, 176 KB

english, 2005

47

New analogues of butylated hydroxytoluene as anti-inflammatory and antioxidant agents

George N. Ziakas, Eleni A. Rekka, Antonios M. Gavalas, Phaedra T. Eleftheriou, Panos N. Kourounakis

Journal:

Bioorganic & Medicinal Chemistry

Year:

2006

Language:

english

File:

PDF, 197 KB

english, 2006

48

Design and study of some novel ibuprofen derivatives with potential nootropic and neuroprotective properties

Ioanna C. Siskou, Eleni A. Rekka, Angeliki P. Kourounakis, Michael C. Chrysselis, Kariofyllis Tsiakitzis, Panos N. Kourounakis

Journal:

Bioorganic & Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 243 KB

english, 2007

49

Synthesis and pharmacological evaluation of amide conjugates of NSAIDs with L-cysteine ethyl ester, combining potent antiinflammatory and antioxidant properties with significantly reduced gastrointestinal toxicity

Dimitrios Galanakis, Angeliki P Kourounakis, Karyophyllis C Tsiakitzis, Christos Doulgkeris, Eleni A Rekka, Antonios Gavalas, Constantina Kravaritou, Christos Charitos, Panos N Kourounakis

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2004

Language:

english

File:

PDF, 255 KB

english, 2004

50

Synthesis and pharmacochemical study of novel polyfunctional molecules combining anti-inflammatory, antioxidant, and hypocholesterolemic properties

Christos M. Doulgkeris, Dimitrios Galanakis, Angeliki P. Kourounakis, Karyofyllis C. Tsiakitzis, Antonios M. Gavalas, Phaedra T. Eleftheriou, Panagiotis Victoratos, Eleni A. Rekka, Panos N. Kourounaki

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2006

Language:

english

File:

PDF, 127 KB

english, 2006

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